Prof. Dr.  Deniz SIGIRLI



B .Sc.:

 Statistics, Anadolu University, (2003)


 Biostatistics, Uludag University, (2006)


 Biostatistics, Uludag University, (2011 )
Statistical & Methodological Publications
Collaborative & Interdisciplinary Publications
Directed Thesis
Statistical & Methodological Publications
Ahmadian R, Ercan ISIGIRLI D, Yildiz A
Combining Binary and Continuous Biomarkers by Maximizing the Area under the Receiver Operating Characteristic Curve
Communications in Statistics - Simulation and Computation (Kabul edildi)
Can FE, Ercan I, SIGIRLI D, Kaya MO, Uysal O
Basic Sampling Methods: What is the Knowledge Level of Academic Staff?
European Journal of Rhinology and Allergy  2019; 2: 1-5
SIGIRLI D, Ercan I, Balcin O, Kaya E.
Adaptation of the Weighted Kaplan-Meier Method to Time-Dependent ROC Curves
Journal of the National Science Foundation of Sri Lanka  2018 46 (1): 11 - 21
Ercan I, SIGIRLI D, Can FE, Ozkaya G, Alper Z.
First Course in Biostatistics at Medical Faculties: Explaining the Importance of Biostatistics
JP Journal of Biostatistics 2017; 14(1):75-84.
Baydili KN, SIGIRLI D.
Comparison of Variance Homogeneity Tests for Different Distributions.
Türkiye Klinikleri Journal of Biostatistics 2017;9(3):197-212
Examining the efficiency of models using tangent coordinates or principal component scores in allometry studies.
Interdisciplinary Sciences: Computational Life Sciences. (2015) 7:3: 249-256
Ercan I, SIGIRLI D,  Ozkaya G
Examining the Variations in the Results of the Hotelling T2 Test in Case of Changing Baseline Landmarks in the Bookstein Coordinates. 
Interdisciplinary Sciences: Computational Life Sciences, (2015) 7:2:186–193
Growth and Allometry in Modern Morphometrics
Türkiye Klinikleri Journal of Biostatistics 2013;5(1):42-8.
Ercan I, Ocakoglu G, Ozkaya G, SIGIRLI D, Cangur S, Gunel Karadeniz P.
An International Survey of Physicians’ Knowledge of Biostatistics
Turkiye Klinikleri Journal of Medical Sciences 2013;33(2):401-9.
Examining Growth with Statistical Shape Analysis and Comparison of Growth Models
Journal of Modern Applied Statistical Methods 2012;11(2):479-92.
Ercan I , Ocakoglu G, SIGIRLI D, Ozkaya G.
Statistical Shape Analysis and Usage in Medical Sciences
Turkiye Klinikleri Journal of Biostatistics,2012;4(1):27-35.
Ercan I, Ocakoglu G, SIGIRLI D,, Ozkaya G
Assessment of Submitted Manuscripts According to Statistical Errors In Medical Sciences
Turkiye Klinikleri Journal of Medical Sciences 2012;32(5):1381-1387.
SIGIRLI D, Ercan I, Jin Y, E. Paksoy, S.Tolunay and I. Tasdelen
Evaluating Cut-off Values with Time-Dependent ROC Curves for Ki67
Pakistan Journal of Statistics 2010;26(4):659-671.
Ercan I, Yazici B, SIGIRLI D, Ediz B, Kan I
Examining Cronbach Alpha, Theta, Omega Reliability Coefficients  According To The Sample Size
Journal of Modern Applied Statistical Methods 2007;6(1):291-303.
Ercan I, Yazici B, Ocakoglu G, SIGIRLI D, Kan I
Review of Reliability and Factors Affecting the Reliability
InterStat, 2007 April, 8
Collaborative & Interdisciplinary Publications
Buyukkoyuncu Pekel N, Yildiz D, Taymur I, Budak E, Ozmen S, Capkur C, Seferoglu M, Gunes A, SIGIRLI D.
Between Olfactory Impairment and Cognitive Functions in Patients with Parkinson Disease.
Arch Neuropsychiatry 2019 (Kabul edildi)
Gur N, Eray S, Makinecioglu I, SIGIRLI D, Vural AP
The relationship of peer bullying with familial expressed emotion and psychopathology
Anatolian Journal of Psychiatry 2020; 21(1): 77-86
Uygun B, Kiyici S, Ozmen S, Gul Z, SIGIRLI D, Cavun S.
The Association Between Olfaction and Taste Functions with Serum Ghrelin and Leptin Levels in Obese Women.
Metab Syndr Relat Disord. 2019; 17 (9): 452-457
Yıldız D, Pekel NB, Yener NP, Seferoğlu M, Günes A, SIGIRLI D,
Assessment of Neurodegeneration by Optical Coherence Tomography and Mini-Mental Test in Parkinson's Disease.
Ann Indian Acad Neurol. 2019 Apr-Jun;22(2):212-216.
Kiyici S, Guclu M, Budak F, SIGIRLI D, Tuncel E.
Even Short-Term Telmisartan Treatment Ameliorated Insulin Resistance But Had No Influence on Serum Adiponectin and Tumor Necrosis Factor-Alpha Levels in Hypertensive Patients with Metabolic Syndrome.

Metab Syndr Relat Disord. 2019 Apr;17(3):167-172.

Akyıldız MY, Ozmen OA, Demir UL, Kasapoglu F, Coskun HH, Basut OI, SIGIRLI D
Should Nasal Function be Considered Prior to Tympanoplasty?
J Int Adv Otol. 2018 Apr;14(1):53-57.
Ozcakir S, SIGIRLI D,, Avsaroglu H.
High wrist ratio is a risk factor for carpal tunnel syndrome.
Clin Anat. 2018 Jul;31(5):698-701.
Sarıhan S, Bayram AS, Gebitekin C, Yerci O, SIGIRLI D,.
Thymic tumors and results of radiotherapy.
Rep Pract Oncol Radiother. 2018 Mar-Apr;23(2):97-104.
Akyıldız MY, Ozmen OA, Demir UL, Kasapoglu F, Coskun HH, Basut OL, SIGIRLI D.
Impact of Septoplasty on Eustachian Tube Functions
J Craniofac Surg. 2017 28(8):1929-1932
Okumus D, Sarihan S, Gozcu S, SIGIRLI D.
The relationship between dosimetric factors, side effects, and survival in patients with non-small cell lung cancer treated with definitive radiotherapy
Med Dosim 2017; 42(3):169-176
Eray S, Vural AP, SIGIRLI D,
School going adolescents' perception of family climate and mental problems: Results from Kocaeli, Turkey
J Pak Med Assoc. 2017 May;67(5):706-710
Sınır GO , Suna S , Inan S , Bagdas D , Tamer CE , Copur OU , SIGIRLI D, Sarandol E , Sonmez G , Ercan I, Evrensel T , Tarım OF , Eren E , Uylaser V , Incedayı B
Effects of long-term consumption of high fructose corn syrup containing peach nectar on body weight gain in sprague dawley rats
Food Science and Technology 2017; 37(2);337-43
Cetinkaya HB, Koksal O, SIGIRLI D, Leylek EH, Karasu O
The predictive value of the modified early warning score with rapid lactate level (ViEWS-L) for mortality in patients of age 65 or older visiting the emergency department.
Intern Emerg Med 2017; 12 (8): 1253-1257
Topyildiz  F, Kiyici S, Gul Z, SIGIRLI D, Guclu M, Kisakol G, Cavun S
Exenatide Treatment Causes Suppression of Serum Ghrelin Levels following Mixed Meal Test in Obese Diabetic Women.
Journal of Diabetes Research 2016 Article ID 1309502, 7 pages
Koksal O, Torun G,  Ahun E, SIGIRLI D, Guney SB, Aydin MO
The comparison of modified early warning score and Glasgow coma scale-age-systolic blood pressure scores in the assessment of nontraumatic critical patients in emergency department.
Niger J Clin Pract 2016;19:761-65.
Alp A, Mengi G, Avsaroglu AH, Mert M, SIGIRLI D
Efficacy of Core-Stabilization Exercise and Its Comparison with Home-Based Conventional Exercise in Low Back Pain Patients.
Turk J Phys Med Rehab 2014;60:36-42.
Topal NB, Orcan S, SIGIRLI D, Orcan G, Eritmen U.
Effects of fat accumulation in the liver on hemodynamic variables assessed by doppler ultrasonography.
J Clin Ultrasound  2015;43(1):26-33.
Ture M, Yıldız M, Karkucak M, Gulten ET, SIGIRLI D, Ozmen AT, Yakut T
Investigation of TNF-alfa gene (G308A) and GSTP1 gene (Ile105Val) polymorphisms in Turkish patients with retinopathy of prematurity
Turkish Journal of Medical Sciences 2015;45(1):164-9.
Yılmaz E, Ayarci AO, SIGIRLI D, Torlar MO, Budak F, Goral G, Oral HB.
Increased serum hepcidin levels in brucellosis.
Clinical Laboratory  2014;60(11):1837-43. 
Ahun E, Koksal O, SIGIRLI D, Torun G, Donmez SS, Armagan E.
Value of Glasgow coma scale predicting the mortality of major trauma patients presenting to the emergency department.
Turkish Journal of Trauma & Emergency Surgery 2014;20(4):241-247.
Kazak E, Akin H, Ener B, SIGIRLI D, Ozkan O, Gurcuoglu E, Yilmaz E, Celebi S, Akcaglar S, Akalin H.
An investigation of Candida species isolated from blood cultures during 17 years in a university hospital.
Mycoses 2014;57(10):623-629.
Aydogan K, Ozakin C, Saricaoglu H, SIGIRLI D, Oral B
Relationship between the interleukin-6-174 gene and mannose-binding lectin codon 54 gene polymorphisms and condyloma acuminatum
European Academy of Dermatology and Venereology 2013;28(10):1306-1312.
Etoz M, Ozdemir ST, SIGIRLI D,, Demirbas AE, Ercan I, Etoz OA, Sisman Y
Evaluation of Bony Structures on Panoramic Radiographs with Statistical Shape Analysis in Patients with Temporomandibular Joint Pain and Limited Mouth Opening.
e-Journal of Dentistry 2013;3(4):495-500
Kose A , Koksal O, Armagan E, SIGIRLI D, Ozdemir F, Akkose S.
Aspirin Resistance in Paitents Presenting to the Emergency Department.
Acta Medica Mediterranea 2013, 29: 247-253.
Demir UL, Cetinkaya B, Karaca S, SIGIRLI D
The Impacts of Adenotonsillar Hypertrophy on Periodontal Health in Children: A Prospective Controlled Pilot Study.
American Journal of Otolaryngology 2013,34(5): 501-4
Bulut M, Cebicci H, SIGIRLI D, Sak A, Durmus O, Top AA, Kaya S, Uz K.
The Comparison of Modified Early Warning Score with Rapid Emergency Medicine Score: A Prospective Multicentre Observational Cohort Study on Medical and Surgical Patients Presenting to Emergency Department.
Emergency Medicine Journal 2014, 31(6): 476-81
Alar T, Ceylan KC, Kaya SO, Sevinc S, SIGIRLI DOzcelik C.
How Does the Type of Thoracotomy Affect the Patient Quality of Life? A Short Form-36 Health Survey Study.
Surgery Today 2014, 44(2): 264-70
Ayarci AO, Yılmaz E, SIGIRLI D, Budak F, Goral G, Oral HB
Diagnostic Value of Serum High Mobility Group Box Protein 1 and Soluble CD163 Levels in Brucellosis
Microbiology and Immunology 2013,57(2):150-8.
Vural P, SIGIRLI D, Eray S, Ercan I, Kilic EZ
The Reliability and Validity Study of Shortened Level of Expressed Emotion Scale in Adolescents
Turkiye Klinikleri Journal of Medical Sciences 2013;33(1):191-9 (in Turkish).
Koksal O, Ozdemir F, Armagan E, Oner N, Sert PC, SIGIRLI D.
Is routine pregnancy test necessary in women of reproductive age admitted to the emergency department?
World Journal of Emergency Medicine 2013;4(3):175-178.
SIGIRLI D, Ozdemir ST,  Ercan I, Taskapilioglu O, Hakyemez B, Sener DK, Zarifoglu M
Statistical Shape Analysis of the Corpus Callosum and the Cerebellum in Migraine Patients

Turkiye Klinikleri Journal of Medical Sciences 2013; 33(1):200-9.

SIGIRLI D, Ercan, I., Ozdemir, S. T., Taskapilioglu O., Hakyemez B., Turan O.F.
Shape analysis of the corpus callosum and the cerebellum in female MS patients with different clinical phenotypes.
The The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 2012; 2957:1202-11.

Oz Gül O, Kıyıcı S, Ersoy C, Cander S, Yorulmaz H, Gül CB, Unal OK, Sarandol E, Kırhan E, SIGIRLI D, Ertürk E, Tuncel E, Imamoğlu S.

Effect of sitagliptin monotherapy on serum total ghrelin levels in patients with type 2 diabetes.

Diabetes Res Clin Pract. 2011;94(2):212-6.

Köksal O, Ozdemir F, Cam Etöz B, Işbil Büyükcoşkun N, SIGIRLI D

Hemostatic effect of a chitosan linear polymer (Celox®) in a severe femoral artery bleeding rat model under hypothermia or warfarin therapy.

Ulus Travma Acil Cerrahi Derg. 2011;17(3):199-204.

Kiyici S, Cander S, Oz Gul O, SIGIRLI D, Kaan Unal O, Duran C, Saraydaroglu O, Ersoy C, Tuncel E, Erturk E, Imamoglu S.
Preoperative parathyroid hormone levels are correlated with parathyroid adenoma volume and bone mineral density but not serum calcium levels.
Minerva Endocrinologica 2011;36(2):123-8.
Kaya E, Paksoy E, Ozturk E, SIGIRLI D, Bilgel H.
Subcutaneous Closed-Suction Drainage Does Not Effect Surgical Site Infection Rate Following Elective  Abdominal Operations: A Prospective Randomized Clinical Trial.
Acta Chir Belg, 2010;110:457-462.
Ozen NS, Ercan I, Irgil E, SIGIRLI D
Anxiety Prevalence and Affecting Factors Among University Students
Asia-Pacific Journal of Public Health, 2010;22(1):127-33.  
Ozdemir ST,  SIGIRLI D, Ercan I, Cankur NS  
Photographic Facial Soft Tissue Analysis of Healthy Turkish Young Adults: Anthropometric Measurements
Aesthetic Plastic Surgery, 2009;33:175-184.
Kiyici S, Ersoy C, Oz Gul O, Sarandol E, Demirci M, Tuncel E, SIGIRLI D, Erturk E, Imamoglu S.
Total and acylated ghrelin levels in type 2 diabetic patients: similar levels observed after treatment with metformin, pioglitazone or diet therapy.
Exp Clin Endocrinol Diabetes. 2009;117(8):386-90.
Kiyici S, Ersoy C, Kaderli A, Fazlioglu M, Budak F, Duran C, Oz Gul O, SIGIRLI D, Baran I, Tuncel E, Erturk E, Imamoglu S.
Effect of Rosiglitazone, Metformin and Medical Nutrition Treatment on Arterial Stiffness, Serum MMP-9 and MCP-1 Levels in Drug Naive Type 2 Diabetic Patients.
Diabetes Research and Clinical Practice, 2009, 86, 44-50.
Ercan I, Ozdemir ST, Etoz A,SIGIRLI D, Tubbs RS, Loukas M, Guney I
Facial asymmetry in young healthy subjects evaluated by statistical shape analysis
J Anat. 2008;213(6):663-9.
Ercan I, Irgıl E, SIGIRLI D, Ozen NS, Kan I
Evaluation of anxiety among medical and engineering students by factor analysis
Studia Psychologica 2008;50(3):267-275.
Batmazoglu M, Evrensel T, Manavoglu O, Dr. Kanat O, SIGIRLI D
The  Evaluation Of The Protective Effect Of Venlafaxine Against Chemotherapy Induced Neuropathy
Turkiye Klinikleri J Med 2008;28(4):425-436.
Kiyici M, Yilmaz M, Akyildiz M, Arikan C, Aydin U, SIGIRLI D, Nart D, Yilmaz F, Ozacar T, Karasu Z, Kilic M
Association between hepatitis B and hepatocellular carcinoma recurrence in patients undergoing liver transplantation.
Transplant Proc. 2008;40(5):1511-7
Kirdak T, Paksoy E, SIGIRLI D, Tasdelen I, Gokgoz S
The effect of distance on the postoperative follow-up of patients with breast carcinoma.
Acta Chir Belg. 2008;108(1):93-7.